Martina Absinta, M.D., Ph.D.

  • 2012-present: Research Fellow, Translational Neuroradiology Section, NINDS

  • MD 2007, Vita-Salute University-San Raffaele Hospital, Milan, Italy
  • Neurology Residency 2012, Vita-Salute University-San Raffaele Hospital, Milan, Italy
  • PhD 2016, Molecular Medicine - Experimental Neurology, Vita-Salute University-San Raffaele Hospital, Milan, Italy
  • About

    Dr. Martina Absinta earned her medical degree (MD), residency in neurology, and PhD in molecular medicine–experimental neurology at Vita-Salute University-San Raffaele Hospital, Milan, Italy. She joined the lab in 2012 and she is currently a research fellow in the Translational Neuroradiology Section, under the mentorship of Dr. Daniel S. Reich. Her research interests include ultra-high-field MRI–pathology correlations in multiple sclerosis, and related identification of novel imaging biomarkers of chronic inflammation (chronic active lesions and meningeal inflammation)

    HONORS AND AWARDS

  • Recipient of National Multiple Sclerosis Society (NMSS) postdoctoral fellowship grant award (2016-2019)
  • Recipient of a Marilyn Hilton Bridging Award from the Conrad N. Hilton Foundation (2017-2022)
  • Selected Publications

    • Absinta M, Sati P, Fechner A, Schindler MK, Nair G, Reich DS. Identification of chronic active multiple sclerosis lesions at 3T MRI. AJNR Am J Neuroradiol. AJNR Am J Neuroradiol. 2018 Jul;39(7):1233-1238. doi: 10.3174/ajnr.A5660. Epub 2018 May 3. PMID:29724768
    • Maggi P*, Absinta M*, Grammatico M, Vuolo L, Emmi G, Carlucci G, Spagni G, Barilaro A, Repice AM, Emmi L, Prisco D, Martinelli V, Scotti R, Sadeghi N, Perrotta G, Sati P, Dachy B, Reich DS, Filippi M, Massacesi L. Central vein sign differentiates Multiple Sclerosis from central nervous system inflammatory vasculopathies. Ann Neurol. 2018 Feb;83(2):283-294. doi: 10.1002/ana.25146. Epub 2018 Feb 15. PMID:29328521 (*equal contribution)
    • Absinta M*, Ha SK*, Nair G, Sati P, Luciano N, Palisoc M, Louveau A, Zaghloul K, Pittaluga S, Kipnis J, Reich DS. Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI. Elife 2017 Oct 3;6. pii: e29738. doi: 10.7554/eLife.29738. PMID:28971799 (*equal contribution)
    • Absinta M, Cortese IC, Vuolo L, Nair G, de Alwis M, Ohayon J, Meani A, Martinelli V, Scotti R, Falini A, Smith B, Nath A, Jacobson S, Filippi M, Reich DS. Leptomeningeal gadolinium enhancement across the spectrum of chronic neuroinflammatory diseases. Neurology 2017 Apr 11:88(15):1439-1444. doi: 10.1212/WNL.0000000000003820.
    • Absinta M, Sati P, Schindler M, Leibovitch E, Ohayon J, Wu T, Meani A, Filippi M, Jacobson S, Cortese I, Reich DS. Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions. J Clin Invest 2016, Jul 1;126(7):2597-609. PMCID: PMC27270171. doi: 10.1172/JCI86198.
    • Absinta M, Sati P, Reich DS. Advanced MRI and Staging of Multiple Sclerosis Lesions. Nature Reviews Neurology 2016, June;12(6):358-68. PMCID: PMC27125632. doi: 10.1038/nrneurol.2016.59.
    • Absinta M*, Vuolo L*, Rao A, Nair G, Sati P, Cortese IC, Ohayon J, Fenton K, Reyes-Mantilla MI, Maric D, Calabresi PA, Butman JA, Pardo CA, Reich DS. Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis. Neurology 2015 Jul 7;85(1):18-28. PMCID: PMC25888557. doi: 10.1212/WNL.0000000000001587.(*equal contribution)
    • Absinta M*, Nair G*, Filippi M, Ray-Chaudhury A, Reyes MI, Pardo CA, Reich DS. Postmortem MRI to guide the pathological cut: individualized, 3D-printed cutting boxes for fixed brains. JNEN 2014; Aug;73(8):780-8. PMCID: PMC25007244. doi: 10.1097/NEN.0000000000000096(*equal contribution)
    • Absinta M, Sati P, Gaitán MI, Maggi P, Cortese IC, Filippi M, Reich DS. Seven-tesla phase imaging of acute multiple sclerosis lesions: A new window into the inflammatory process. Ann Neurol. 2013; 74(5): 669-678. PMCID: PMC23813441. doi: 10.1002/ana.23959.
    • Absinta M, Rocca MA, Moiola L, Copetti M, Milani N, Falini A, Comi G, Filippi M. Cortical lesions in children with multiple sclerosis. Neurology 2011; 76(10): 910-913. PMCID: PMC21383327. doi: 10.1212/WNL.0b013e31820f2e69.
    • Absinta M, Rocca MA, Moiola L, Ghezzi A, Milani N, Veggiotti P, Comi G, Filippi M. Brain macro- and microscopic damage in patients with paediatric MS. J Neurol Neurosurg Psychiatry (JNNP) 2010; Dec;81(12):1357-62. PMCID: PMC20660915. doi: 10.1136/jnnp.2010.205682.