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Motor Neuron Diseases

  • Program Duration: 1-3 years

    This fellowship provides an opportunity to engage in research on the physiology, quantitative imaging, and genetics of motor neuron disorders. Current studies are directed at characterizing clinical features of rare motor neuron disease variants and assessing markers of disease progression. Methodologies include functional and structural multimodal MRI, transcranial magnetic stimulation, and motor unit studies. Fellows gain hands-on experience with clinical research methodology and may take coursework to obtain an NIH certificate in clinical research. 

    Areas of Current Research

• Natural history and biomarkers of C9orf72 associated Amyotrophic lateral sclerosis and frontotemportal dementia
• Natural history, imaging, and genetics of primary lateral sclerosis
• Endogenous Retroviruses in ALS

Faculty 

Mary Kay Floeter, M.D., Ph.D., Chief, Motor Neuron Disorders Unit, NINDS, floeterm@ninds.nih.gov

Bryan Traynor
, M.D., Ph.D., Neuromuscular Diseases Research Unit, Laboratory
of Genetics, NIA,
traynorb@mail.nih.gov

Avindra Nath, M.D., Chief, Section of Infections of the Nervous System, NINDS. natha@mail.nih.gov

Reghan Foley, M.D., Staff Clinician, Neuromuscular and Neurogenetic Disorders of Childhood Section, Neurogenetics Branch, reghan.foley@nih.gov