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Parkinson’s Disease

Parkinson's disease (PD) is a degenerative disorder of the central nervous system that belongs to a group of conditions called movement disorders.  It is both chronic, meaning it persists over a long period of time, and progressive, meaning its symptoms grow worse over time. Medical treatment of PD focuses on improving motor symptoms using medications, surgery, and behavior modifications, such as increasing physical activity.

The Parkinson's Clinic provides a neurological examination to determine eligibility for research studies. Research studies involve a series of tests that may include a genetic blood sample (LRRK2), memory testing, Smell Identification Testing (SIT), and a neurological evaluation. Eligible patients must have on hand a copy of their medical record or letter of referral from a physician that includes a summary of pertinent medical information related to the neurological condition. This would include when the condition was first noted, how it was presented, the current status, and listing of treatments/medications and their effect.

If you are interested in participating in one of our research studies, please contact and submit your medical record/letter of referral to:

Mae P. Brooks
Patient Care Coordinator
Parkinson Clinic
Office of the Clinical Director
National Institute of Neurological Disorders and Stroke
CRC Room 5-1469 NE
10 Center Drive, Bethesda, Maryland 20892
Phone: (301) 496-4604 or 800-362-3479
Fax: (301) 496-6609
brooksm@ninds.nih.gov

OR

Patient Recruitment and Public Liaison Office
Toll-free at:1-800-411-1222
TTY: 1-866-411-1010


Parkinson’s Disease Care Providers at NIH:
Physicians

  Mark Hallett Codrin Lungu
Debra Ehrlich, MD
Chief, Parkinson's Clinic
Mark Hallett, MD
Chief, Human Motor Control Section
Codrin Lungu, MD
Program Director, Division of
Clinical Research


Nurse Practitioners

Dr. Irene Dustin
Irene Dustin, PhD, CRNP

Coordinators
 
Mae P. Brooks

Studies Actively Recruiting Patients:
01-N-0206   Phenotype/Genotype Correlations in Movement Disorders
14-N-0086   Deep Brain Stimulation in Movement Disorders
11-N-0211    Deep Brain Stimulation for Movement Disorder
12-N-0137   A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease
17-N-0076   Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease
93-N-0202  Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions
16-N-0166  Deep Brain Stimulation Surgery for Treatment of Focal Hand Dystonia

For more information on Parkinson’s Disease:

https://www.ninds.nih.gov/Disorders/All-Disorders/Parkinsons-Disease-Information-Page


Related Links:
ClinicalTrials.gov