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Office of the Clinical Director

Dr. Avi NathDr. Avi Nath joined NIH as the Clinical Director of NINDS in February 2011. Prior to this, he was the Director of the Division of Neuroimmunology and Neurological Infections at Johns Hopkins University for 9 years. His current responsibilities are to oversee and build the clinical research program at NINDS. He also the Director of the Translational Neuroscience Center. The office has a clinical trials unit that provides assistance in all stages of protocol development and monitoring. It also oversees a unique training program for clinical fellows and residents in Neurology and Neurosurgery. The office also oversees a variety fo specialized clinics and provides services for investigation and consultation for patients with neurological disorders.

He graduated from Christian Medical College in Ludhiana, India, in 1981, completed a residency in Neurology in 1986 and a fellowship in Neuroimmunology from University of Texas in Houston in 1988. He was a clinical fellow in Neurovirology at NINDS from 1988-90. He held faculty positions at University of Manitoba (1990-97), University of Kentucky (1997-2002) and at Johns Hopkins University (2002-11).  

His research has focused on the neuropathogenesis, neurological manifestations and treatment of HIV infection, Progressive Multifocal Leukoencephalopathy and Multiple Sclerosis. He has published over 300 articles and reviews. He has served on the editorial board of several journals and is currently is the Associate Editor of the Journal of Neurovirology and has edited a book on Clinical Neurovirology. 

He is the past Chair of the Section of Neuroinfectious Diseases of the American Academy of Neurology and the current President of the International Society of Neurovirology. 

The Clinical Neuroscience Program (CNP)

The CNP is comprised of clinical research groups organized within a multitude of branches, sections, units and clinics focusing on disease mechanisms and treatment of a variety of neurological disorders. The research methods within each group range from molecular biology, biochemistry, cell biology, immunology, genetics, pharmacology, neurophysiology, imaging to clinical trials. The program offers a unique environment for clinicians and physician-scientists working within the NIH Clinical Center, the nation’s largest hospital devoted entirely to clinical research and a unique training environment for the next generation of clinician-scientists. As a whole the program works to expedite the translation of scientific discoveries into new approaches for diagnosing, treating and preventing neurological disease and disorders. A large number of clinical studies are currently ongoing in a variety of neurological disorders; details of which can be accessed through

Contact Information

Office of the Clinical Director, NINDS, NIH 
10 Center Drive, Bldg. 10, Rm. 7C103
Mail Stop 1430
Bethesda, MD 20892
Phone: (301) 496-1561
Fax: (301) 402-1007

Past Clinical Directors: 
Mary Kay Floeter, M.D., Ph.D. (Acting) 2007-2011
Henry McFarland, M.D. 2001-2007
Guy McKhann, M.D. 2000-2001
Mark Hallett, M.D. 1984-2000
Paul Kornblith, M.D. (Acting) 1983
Dale McFarlin, M.D. (Acting) 1982
Donald Calne, D.M. 1974-1981
John van Buren, M.D. (Acting) 1971-1974
Maitland Baldwin, M.D. 1961-1970
G. Milton Shy, M.D. 1953-1960

Assistant Clinical Directors:
Dr. Tanya Lekhy, Assistant Clinical Director of Medical Affairs
Dr. Dietrich Haubenberger, Assistant Clinical Director of Clinical Research
Dr. Omar Khan, Assistant Clinical Director of Medical Education

Under the Office of the Clinical Director is the Clinical Trials Unit
Directed by Dr. Dietrich Haubenberger
The Clinical Trials Unit provides assistance with protocol navigation, regulatory affairs, data management, 
biostatistics and bioinformatics, and in trial design and monitoring of early phase clinical trials.