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Movement Disorders Clinic 

Movement disorders can be defined as neurologic syndromes in which there is either an excess of movement (commonly known as hyperkinesia, dyskinesia, and abnormal involuntary movement) or a lack of voluntary and automatic movements unrelated to weakness or spasticity.  These complex disorders may or may not have genetic, environmental, infectious, metabolic, nutritional, toxicological, and vascular factors contributing to their cause.  One of the most common movement disorders is Parkinson’s disease, which is a slow progressive disorder characterized by tremor, slowness of movement, and difficulty walking.  Examples of other types of movement disorders include the following:  Dystonia, Chorea, Huntington's disease, Ataxia, Tremor and Essential tremor, Myoclonus, Tics, Tourette syndrome, Restless legs syndrome, Stiff person syndrome, Gait disorders, and Spasticity. 

Researchers at the National Institutes of Health (NIH) are pursuing studies with an overall focus and goal of understanding the natural history of movement disorders and finding their causes.  Our natural history study is the primary study through which we screen all patients with neurological conditions to enroll in additional research protocols in the Human Motor Control Section (HMCS), Medical Neurology Branch (MNB).  No investigational treatments will be administered on this primary study and the NIH physicians will be playing a consultative role to the patient’s primary physician.  The majority of our other studies involve techeniques such as Magnetic Resonance Imaging (MRI), Transcranial Magnetic Stimulation (TMS), Electroencephalography (EEG), and Magnetoencephalography (MEG), to better understand various characteristics of the brain.  A limited number of studies do involve treatment.  For example, some studies utilize techniques that examine the effectiveness of botulinum toxin as treatment for a variety of movement disorders, offering botulinum toxin on a limited basis.   Researcher also collaborate with the neurosurgery department utilizing Deep Brain Stimulation (DBS) for patients with specific disorders.

If you are a patient interested in treatments for movement disorders or participating in one of our research studies, please contact:

Elaine Considine, RN, BSN
Clinical Research Nurse
Division of Intramural Research (DIR)
Medical Neurology Branch (MNB)
Building 10, Room 7D36
National Institute of Neurological Disorders and Stroke (NINDS)
Phone: 301-435-8518
Fax: 301-480-2286
Email: considinee@ninds.nih.gov

OR

Patient Recruitment and Public Liaison Office toll-free at:
1-800-411-1222
TTY: 1-866-411-1010

Movement Disorders Care Providers at NIH:

Physicians:
 Mark Hallet   Codrin Lungu
 Mark Hallett, M.D., Chief,
Human Motor Control Section

Debra Ehrlich, M.D.
Chief, Parkinson' s Clinic
Codrin Lungu, M.D.
Program Director,
Division of Clinical Research
 Dietrich Haubenberger
Karin Mente
 Dietrich Haubenberger, M.D., Chief
Clinical Trials Unit
 Sonja Scholz, M.D., PhD
Neurogenetics Branch
  Karin Mente, M.D.
Clinical Fellow
 
 Carine Maurer Emmanuel Akano  
Carine Maurer M.D. Ph.D.
Clinical Fellow
Emmanuel Akano, M.D.
Clinical Fellow
Omar Ahmad, M.D.
Clinical Fellow
  
 Shabbir Hussain    
Shabbir Hussain Merchant, M.D.
Clinical Fellow
Imran Khan, M.D.
Clinical Fellow

 

 

Nurse Practitioners:

Shashi Ravindran, CRNP

Patient Care Coordinator:

Barbara Kimber


Studies Actively Recruiting Patients:


93-N-0202: Diagnosis and History Study of Patients with Different Neurological Conditions (NINDS/MNB)
07-N-0190: Neurobiology of Psychogenic Movement Disorder and Non-Epileptic Seizures (NINDS/MNB)
01-N-0206: Phenotype/Genotype Correlations in Movement Disorders (NINDS/MNB)
85-N-0195: Botulinum Toxin for the Treatment of Involuntary Movement Disorders (NINDS/MNB)
15-N-0035: Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and Spasticity (NINDS/MNB)
11-N-0157: Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders (NINDS/MNB)
09-N-0118: Investigation of Neurofeedback with Real-Time fMRI in Healthy Volunteers and Patients with Hyperkinetic Movement Disorders (NINDS/MNB)
16-N-0064:  Cholinergic Receptor Imaging in Dystonia (NINDS/MNB)
13-N-0076: Transcranial Magnetic Stimulation for Focal Hand Dystonia (NINDS/MNB)

For more information on Movement Disorders:

https://www.ninds.nih.gov/disorders/movement disorders 

Related Links:
www.clinicaltrials.gov