Clinical Investigations Section, Stroke Branch (SB), NINDS
John Hallenbeck, M.D., Chief
Stroke Diagnostics and Therapeutics Section (SDTS)
Stroke Branch (SB), NINDS
John Hallenbeck, M.D., Acting Chief
Larry Latour, Ph.D., Senior Scientist
Ms. Patricia Lyall, Program Coordinator
The SDTS, established under the direction of Dr. Steven Warach in 1999, is a member of the NINDS SPOTRIAS network of stroke translational research centers. The section conducts clinical research at the Stroke Centers of Suburban Hospital in Bethesda, MD and the Washington Hospital Center in Washington, D.C., where the NINDS has placed stroke teams and magnetic research imaging (MRI) research facilities.
The section's research efforts pioneered the routine clinical use of diffusion and perfusion MRI in ischemic stroke, performed seminal studies defining the human ischemic penumbra with MRI, and introduced innovative uses of MRI into stroke clinical trial design. The section's current research focus is on novel diagnostic and therapeutic approaches to acute brain injury: acute ischemic stroke, blood-brain barrier disruption, and traumatic brain injury. The section also conducts laboratory research in stroke, with experimental models closely approximating clinical imaging and clinical trial variables, providing reciprocal influences between the bench and bedside investigations. A major research interest of the section is to delineate biomarkers for drug development to treat and/or prevent stroke.
Neuro Vascular Brain Imaging Unit, Stroke Branch (SB), NINDS
Richard Leigh, M.D., Assistant Clinical Investigator