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Epilepsy

Program Duration: 2 years

FROM LEFT TO RIGHT: MEG spike source localization: dipole field map; MEG/EEG tracing; Magnetic source imaging



The Clinical Epilepsy Section (CES) offers an integrated two-year program in collaboration with the EEG Laboratory. In the year spent in the CES, Fellows have primary responsibility for the care of patients studied on the video-EEG monitoring unit. They evaluate new patients in the outpatient clinic and follow selected patients. They participate in research on surgical evaluation, antiepileptic drug trials, PET, fMRI, and magnetoencephalography (MEG). In the year spent in the EEG Laboratory, Fellows receive formal training in EEG, evoked potentials, and polysomnography. The second year is affiliated with the Walter Reed National Military Medical Center and Children’s National Medical Center, fulfills requirements for the American Board of Psychiatry and Neurology Added Qualification in Clinical Neurophysiology.

Area of Current Research

fMRI studies of language and memory in epilepsy
PET imaging of inflammation, as well as serotonin and benzodiazepine receptors
MEG for seizure focus localization
Antiepileptic drug trials using novel agents
Convection-enhanced delivery of muscimol to treat epilepsy
Electrophysiological (ECoG and single unit activity) correlates of cognition and behavior
Decoding electrophysiological seizure markers and predictors

Faculty

William H. Theodore, M.D., Chief, Clinical Epilepsy Section, theodorw@ninds.nih.gov

William D. Gaillard, M.D., Child Neurologist, Clinical Epilepsy Section, gaillardw@ninds.nih.gov

John Heiss, M.D., Staff Clinician, Surgical Neurology Branch, heissj@ninds.nih.gov

Omar Khan, M.D., Staff Clinician, Epileptologist, Clinical Epilepsy and EEG Sections, omar.khan@nih.gov

Sara Inati, M.D., Chief, Electroencephalography Section, inatisk@mail.nih.gov

Kareem Zaghloul, M.D., Chief, Functional and Restorative Neurosurgery Unit, Surgical Neurology Branch, zaghloulka@mail.nih.gov