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Sadhana Jackson

Sadhana Jackson, M.D.

Assistant Clinical Investigator

M.D., Eastern Virginia Medical School

Clinical interests: Pediatric neuro-oncology, Pharmacology, Pediatric oncology

Research interests: Blood-brain barrier, Brain Tumors, Pharmacology, Vascular biology

Dr. Jackson attended Hampton University where she received her Bachelor of Science in Molecular Biology. She then obtained her MD from Eastern Virginia Medical School (EVMS). Dr. Jackson subsequently completed a residency in Pediatrics at Orlando Health and then completed a three-year fellowship in pediatric hematology/oncology at St. Jude Children’s Research Hospital. Additionally, she completed a two-year joint fellowship in pediatric neuro-oncology and clinical pharmacology at Johns Hopkins Medical Institute before being selected as an NCI Assistant Clinical Investigator in the Clinical Investigator Development Program in 2015.

Dr. Sadhana Jackson is a board-certified pediatrician and pediatric hematologist/oncologist with clinical expertise and research efforts related to the blood-brain barrier and malignant glioma. Dr. Jackson’s clinical practice focuses on drug delivery of systemic agents for pediatric malignant brain tumor patients. She has extensive experience with use of intracerebral microdialysis to evaluate optimal drug entry in malignant tumors.

As an Investigator in NINDS, Dr. Jackson ties her clinical practice to her research efforts focused on understanding the heterogeneous permeability of the blood-brain barrier amongst malignant gliomas. With her laboratory and clinical studies, her team aims to modulate the tumor microenvironment to enhance effective treatments to the CNS for malignant gliomas. Using exquisite tools to measure drug concentrations and agents to transiently disrupt the BBB, her research aims to maximize therapies for prolonged survival in aggressive pediatric brain tumors.

    Education & Training:

  • Pediatric Neuro-oncology Fellowship, Johns Hopkins Medical Institute, 2013-2015
  • Pediatric Hematology/Oncology Fellowship, St. Jude Children’s Research Hospital, 2010-2013
  • Pediatric Residency, Orlando Health, 2007-2010
  • M.D., Eastern Virginia Medical School, 2003-2007
  • BS, Hampton University, 1999-2003

    Clinical Interests:

  • Chiari I malformation
  • Syringomyelia
  • Neurofibromatosis type 2 (NF2)-associated peripheral nerve tumors
  • Brain tumor treatment using functional mapping and intraoperative MRI
  • Gene therapy for Parkinson’s disease
  • Intrathecal injection of resiniferatoxin (RTX) for intractable cancer pain

    Clinical Interests:

  • Pediatric neuro-oncology
  • Pharmacology
  • Pediatric oncology

    Organization and Professional Memberships:

  • Member, American Board of Pediatrics

    Honors and Awards:

  • SNO Young Investigators Award, 2019
  • NIH Distinguished Scholar, 2018
  • NIH Clinical Investigator Development Program Scholar, 2015

For additional publications, please click here.