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Dr. Chittiboina

Prashant Chittiboina, MD, MPH

Assistant Clinical Investigator

M.D., Goa University

Residency, Neurological Surgery, LSU Health Sciences Center at Shreveport

Clinical interests: pituitary tumors, brain tumors, skull base surgery, spinal tumors

Research interests: von Hippel-Lindau disease clinical research, pituitary tumor research

Dr. Chittiboina was born in India where he completed his medical training at Goa University (India) in 2000. He was awarded Master of Public Health from Idaho State University in 2004. He completed a general surgery Internship at Bronx Lebanon Hospital, New York and a clinical neurosurgery fellowship at the University of Washington, Seattle. He completed his residency in neurosurgery at Louisiana State University, Shreveport in 2012. During residency, he spent a year in the lab studying neuro-vascular disease with a fellowship grant. He came to the NIH in 2012 as a Pituitary and Neuroendocrine Surgery fellow. Dr. Chittiboina was trained by Dr. Edward H. Oldfield and Dr. Russell R. Lonser during his fellowship. He was later recruited as a Staff Clinician within the Surgical Neurology Branch in 2013. In 2015, he was awarded Assistant Clinical Investigator position within the NINDS allowing him to start the Neurosurgery Unit for Pituitary and Inheritable Diseases (NUPID). Dr. Chittiboina is married to a physician, has one child, and runs/bikes for leisure.

Dr. Chittiboina is a neurosurgeon specializing in pituitary and skull base tumors. He works closely with Endocrinology services (from Eunice Kennedy Shriver National Institute of Child Health and Disease – NICHD) to diagnose and treat rare hormone secreting pituitary microadenomas. Dr. Chittiboina treats both adult and pediatric patients with Cushing’s disease, and other pituitary conditions. Along with the Endocrine services, Dr. Chittiboina’s pituitary practice in Cushing’s disease amounts to one of the highest volumes around the world. Dr. Chittiboina’s skull base surgery practice extends to taking care of inheritable tumors syndromes including von-Hippel Lindau disease and Neurofibromatosis 2. Patients with Neurofibromatosis 2 present with challenging tumors including vestibular schwannomas, cranial nerve tumors, meningiomas and spinal cord ependymomas. Dr. Chittiboina performs posterior fossa and spinal cord surgeries to remove these tumors. Patients von Hippel Lindau syndrome present with hemangioblastomas and endolymphatic sac tumors in similar locations needing posterior fossa and spinal cord surgeries.

    Education & Training:

  • Fellowship, Surgical Neurology Branch, NINDS, Neuroendocrine and Pituitary Surgery, July 2012 – June 2013
  • Chief Resident, Department of Neurosurgery, Louisiana State University at Shreveport, July 2011 – June 2012
  • Malcolm Feist Cardiovascular Research Fellow, Department of Neurosurgery, Louisiana State University at Shreveport, July 2010 – June 2011
  • Resident Physician, Department of Neurosurgery, Louisiana State University at Shreveport, July 2006 – June 2011
  • Clinical Fellow, Department of Neurosurgery, University of Washington, July 2005 – June 2006
  • Surgical Intern, Department of Neurosurgery, Bronx Lebanon Hospital Center, July 2004 – June 2005
  • MPH, Idaho State University, August 2001 – May 2004
  • Junior Resident, Department of Dermatology, Goa Medical College, India, September 2000 – June 2001
  • Junior Resident, Department of Neurosurgery, Goa Medical College, India, March 2000 – September 2000
  • Rotating Intern, Goa Medical College Hospitals, India, January 1999 – December 1999
  • M.B.B.S., Goa Medical College, India, August 1994 – November 1998

    Clinical Interests:

  • Pituitary lesions
  • Skull Base Tumors

    Professional Memberships:

  • Member, Young Neurosurgeon Committee (YNC), AANS, 2010 – 2012
  • Chair, Neurosurgery Top-Gun Subcommittee of YNC, AANS, 2010 – 2012
  • Socioeconomic Fellow, Southwest Quadrant, CSNS, 2011 – 2012
  • Liaison, Stereotactic and Functional Section, AANS/CNS, 2011 – 2012
  • Member, AANS/CNS Guidelines Committee on Brain Death, 2012 – 2013
  • Member, CNS Information Technology Committee, 2012 – 2014
  • Grant Reviewer, Brain Tumor Initiative, UK, 2014

    Honors & Awards:

  • Integra Foundation Award, AANS/CNS Tumor Section, 2016
  • American Brain Tumor Association Young Investigator Award, AANS/CNS Tumor section, 2015
  • Galbraith Award for Cerebrovascular surgery topic, CNS Annual Meeting, 2011
  • Malcolm Feist Cardiovascular Research Fellowship (Intramural grant), 2010
  • Second Place Scientific E-poster, AANS Annual Meeting, Cerebrovascular category, 2009
  • Third Place Scientific E-poster, AANS Annual Meeting, Spine and Peripheral Nerve category, 2008

Selected Publications:

  • Lu J, Chatain GP, Bugarini A, Wang X, Maric D, Walbridge S, Zhuang Z, Chittiboina P. Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease. J Clin Endocrinol Metab. 2017 Aug 1;102(8):2825-2835. doi:10.1210/jc.2017-00464. PubMed PMID: 28505327; PubMed Central PMCID: PMC5546859.
  • Asuzu D, Chatain GP, Hayes C, Benzo S, McGlotten R, Keil M, Beri A, Sharma ST, Nieman L, Lodish M, Stratakis C, Lonser RR, Oldfield EH, Chittiboina P. Normalized early post-operative cortisol and ACTH values predict nonremission after surgery for Cushing's disease. J Clin Endocrinol Metab. 2017 Mar 15. doi:10.1210/jc.2016-3908. [Epub ahead of print] PubMed PMID: 28323961.
  • Chittiboina P, Talagala SL, Merkle H, Sarlls JE, Montgomery BK, Piazza MG, Scott G, Ray-Chaudhury A, Lonser RR, Oldfield EH, Koretsky AP, Butman JA. Endosphenoidal coil for intraoperative magnetic resonance imaging of the pituitary gland during transsphenoidal surgery. J Neurosurg. 2016 Dec;125(6):1451-1459. Epub 2016 Mar 18. PubMed PMID: 26991390; PubMed Central PMCID: PMC5093080.
  • Chittiboina P, Montgomery BK, Millo C, Herscovitch P, Lonser RR. High-resolution(18)F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging for pituitary adenoma detection in Cushing disease. J Neurosurg. 2015 Apr;122(4):791-7. doi:10.3171/2014.10.JNS14911. Epub 2014 Dec 5. PubMed PMID: 25479121; PubMed Central PMCID: PMC5091074.
  • Sizdahkhani S, Feldman MJ, Piazza MG, Ksendzovsky A, Edwards NA, Ray-Chaudhury A, Maric D, Merrill MJ, Pacak K, Zhuang Z, Chittiboina P. Somatostatin receptor expression on von Hippel-Lindau-associated hemangioblastomas offers novel therapeutic target. Sci Rep. 2017 Jan 17;7:40822. doi: 10.1038/srep40822. PubMed PMID: 28094316; PubMed Central PMCID: PMC5240113.
  • Feldman MJ, Sizdahkhani S, Edwards NA, Merrill MJ, Ray-Chaudhury A, Zhuang Z, Lonser RR, Oldfield EH, Chittiboina P. Loss of Quiescence in von Hippel-Lindau Hemangioblastomas is Associated with Erythropoietin Signaling. Sci Rep. 2016 Oct 17;6:35486. doi: 10.1038/srep35486. PubMed PMID: 27748427; PubMed Central PMCID: PMC5066214.

For complete publication list, please click here.