Lucy Forrest - Prototype 01

Forrest Lab

National Institute of Neurological Disorders & Stroke


Forrest Lab Website

The Forrest lab, led by NIH Investigator Dr. Lucy R. Forrest, uses computational approaches to study proteins that exist in cell membranes. We are particularly interested in understanding the function of coupled transporter proteins through an understanding of their structure. We also develop methods to better enable the prediction of functionally important properties of such proteins. See our "Software & Data" link for more details.

The group was set up in the Max Planck Institute for Biophysics in Frankfurt, Germany, in 2007, and moved to the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) in Bethesda, MD, USA in 2013. Currently the lab comprises 3 postdocs, and two post-baccalaureate fellows. Follow our "Lab Members" link for more details.

Useful Links:

  • Forrest group profile at NINDS - with information about Research Interests
  • The Faraldo Lab (faraldolab.org) - Our colleagues in the Theoretical Molecular Biophysics Section of NHLBI.

Lab News

Benchmarking membrane protein symmetry

Congratulations to Dr. Antoniya Aleksandrova for her elegant work creating a benchmark of membrane protein symmetries, just accepted for publication!

Serotonin uptake in gut bacteria?

Recent work with the Hsaio lab shows an intriguing role for serotonin in gut microbe colonization potentially involving transporter-mediated uptake. Congratulations to Dr. Antoniya Aleksandrova & summer student Noah Riley! 

Hitchhiking on lysosomes

Human annexin protein connects lysosomes to RNA granules, with implications for ALS. Congratulations to summer student Matthew and postbac Christina Stephens!

Lucy honored to present the NIH Directors Seminar

Her talk on April 5th titled "Satisfying symmetry: uncovering functional insights from patterns in membrane protein structures" can be viewed here.

 

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