Lucy Forrest - Prototype 01

Forrest Lab

National Institute of Neurological Disorders & Stroke

Contact

Computational Structural Biology Unit
National Institute of Neurological Disorders and Stroke (NINDS)
National Institutes of Health (NIH)
35 Convent Drive, Rm 3D991 MSC 3761
Bethesda
MD 20892-3761
USA
Telephone: +1-301-402-2012
Fax: +1-301-480-1720
E-mail: lucy.forrest(at)nih.gov

Lab News

Lucy honored to present the NIH Directors Seminar

Her talk on April 5th titled "Satisfying symmetry: uncovering functional insights from patterns in membrane protein structures" can be viewed here.

Simulations help characterize transporter conformations

Paper out now in J. Gen. Physiol! We used simulations with EBmetaD to rank transporter conformations according to their agreement with DEER distance distributions. In collaboration with the Ziegler and Prisner labs, with thanks the Faraldo-Gómez lab!

EncoMPASS is in the Nucleic Acids Research database issue

Read about our new database, EncoMPASS, an easy new interface and resource to analyze symmetries and relationships between membrane protein structures!

New insights into coupling during symport

A recent collaboration with Gary Rudnick has just been accepted for publication. We identify a key molecular interaction responsible for responding to bound ligands and required for the major transport-related conformational change. See it in the bioRxiv here.

 

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