Compulsive behaviors are repeated, perseverative actions that are difficult to inhibit despite clear intentions and harmful consequences for the patients. While their expression is diverse – ticks, compulsive eating, and addiction are all examples — compulsive behaviors are driven by shared neuro-circuitry that must be studied from the genetic and molecular level to system-based and behavioral expression. The CCB’s mission is to understand the neurobiology of complex behaviors that result in these compulsive and repetitive actions, and to develop and test new therapeutics aimed at alleviating or reversing these behaviors. By understanding the processes that promote or inhibit the development of compulsive behaviors, we can not only optimize existing treatments, but also for design new pharmacological and behavioral interventions.
The CCB is striving to advance scientific discovery in the field of compulsive behaviors and to develop expertise on the topic within the NIH Intramural Research Program (IRP). By bringing together basic scientists and clinical researchers from seven different Institutes, the Center fosters collaboration within the IRP neuroscience community, provides unique opportunities for research crossover and networking, and trains future experts in the field of compulsive behaviors.
The CCB was launched in 2017 with funding from the 2017 DDIR Innovation Award, and continued to be funded through the 2018 DDIR Challenge Innovation Award Program.
Since 2019, the CCB receives direct funding from the main IC's involved (NICHD, NIDA, NIDDK, NIEHS, NINDS, NIMH, and NIAAA) allowing for a longer term commitment to collaborative research projects focused on compulsive behaviors.
The new application cycle opens on March 2nd, 2020! Submission deadline is March 30th, 2020. Please see the details of the call on the fellowship application page.
The CCB is looking to fund outstanding candidates, both clinical or basic science researchers, who are interested in studying topics aligned with the mission of the CCB and with a strong desire for interactions and collaborations with the labs in the IRP. Applications are open for current graduate students, postdoctoral IRTA fellows in the IRP, or incoming postdoctoral fellows joining the IRP laboratory before September 30, 2020.
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