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Postdoc Opening

Investigator: Andres Buonanno, Ph.D.
Affiliation:Molecular Neurobiology Section
Position Type:Postdoctoral Fellowship
Description:

A position is available to study the role of the Neuregulin (NRG) signaling pathway in synapse development and plasticity, and its possible role in psychiatric disorders. At present, NRG-1 is the gene showing the highest association as a risk factor for schizophrenia. We have recently shown that NRG acutely regulates plasticity at  hippocampal CA3 --> CA1 glutamatergic synapses by selectively reducing AMPA, but not NMDA, receptor EPSCs.  Using AMPA receptors tagged with a pH-sensitive variant of GFP, we demonstrated in live neurons that NRG causes the rapid internalization of surface AMPARs.  Our lab uses a variety of experimental techniques, which include transgenic and knock-out mice, live-imaging, electrophysiology and classical molecular biology techniques. Candidates with electrophysiology experience are encouraged to apply.

Application Instructions:

Please send your curriculum vitae, Letter of Interest and three reference letters to:

Andrés Buonanno, Ph.D.
Section on Molecular Neurobiology, NICHD, NIH
Building 35, Room 2C-1000
35 Lincoln Drive
National Institutes of Health
Bethesda, MD 20892-3714

Email: buonanno@helix.nih.gov

  • Andres Buonanno, Ph.D.
  • Senior Investigator
  • Porter Neuroscience Research Center
  • 35 Convent Drive 35, 2C-1000
  • Bethesda, MD 20892-0001
  • Office: 301-496-0170
  • Fax:
  • Lab :
  • NIH AND DHHS ARE EQUAL OPPORTUNITY EMPLOYERS

  • The Last Update : 5/8/2012