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NINDSNIMHNICHDNIDCDNEINIDCRNIANIAAANIDANHGRI NCCIHNIDDKNIEHSCCB

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Senior Investigator

Richard S. Chadwick, Ph.D.

Laboratory of Cellular Biology
Building 10 Room 5D49
10 Center Drive MSC1417
Bethesda MD 20892-1417
Office: (301) 435-1957

Fax: (301) 480-1716
chadwick@helix.nih.gov

Dr. Chadwick received B.S. and M.S. degrees from Cornell University. He received his Ph.D. from Stanford University in 1971, where he studied light scattering phenomena in blood. Dr. Chadwick joined the engineering faculty at the Technion Israel Institute of Technology in 1971 where he began his studies on cochlear mechanics. He moved to UCLA as an assistant professor in 1975 where he continued this work with Julian Cole. Dr. Chadwick joined the Bioengineering and Instrumentation Branch at NIH in 1980, where he began research in cardiovascular dynamics, and then moved to the NIDCD as a Senior Investigator in 1996. He is an elected fellow of the American Institute of Medical and Biological Engineering. Dr. Chadwick's laboratory is studying the biomechanics of cochlear fine-tuning.



The aim of the Section on Auditory Mechanics is to improve basic understanding of the auditory periphery through the combined use of mathematical modeling of cochlear macro, micro, and nano mechanics together with structural, biophysical and physiological data.

We are studying the radial structure of the cochlear traveling wave by comparing radial modes computed from our fluid-solid interaction finite element code with video micrographs obtained from the hemicochlea preparation that are analyzed by our optical flow motion analysis code.

We are currently developing atomic force microscopy techniques for both imaging and measurement of mechanical properties of tissue isolated from the mammalian cochlea. These data will be incorporated into our modeling studies.

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  • Hongxue Cai, Ph.D.
    Senior Research Fellow
    (301) 451-6383

  • Brett Shoelson, Ph.D.
    Senior Research Fellow

  • 1) Chadwick, RS (2001)
  • Axisymmetric indentation of a thin incompressible elastic layer
  • SIAM J. Applied Math
  • 2) Chadwick, RS, Manoussaki, D (2000)
  • Geometric wave amplification in a helicoidal version of the classical model of cochlear mechanics
  • , In: Wada, H. et al. (Eds.) Recent Developments in Auditory Mechanics. World Scientific, 195-201
  • 3) Manoussaki, D, Chadwick, RS (2000)
  • Effects of geometry on fluid loading in a coiled cochlea
  • SIAM J. Applied Math , 61, 369-386
  • 4) Dimitriadis, EK, Chadwick, RS (1999)
  • Solution of the inverse problem for a linear cochlear model: a tonotopic cochlear amplifier
  • J. Acoust. Soc. Am. , 106, 1880-1892
  • 5) Chadwick, RS (1998)
  • Compression, gain, and nonlinear distortion in an active cochlear model with sub-partitions
  • Proc. Nat. Acad. Sci. USA , 95, 14594-14599
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