Neuroscience@NIH > Faculty

Investigator

Karen Faith Berman, M.D.

Clinical Brain Disorders Branch, NIMH
Building 10 Room 4C101

10 Center Drive MSC1365
Bethesda MD 20892-1365

Office: (301) 496-7603

Fax: (301) 496-7437
karen.berman@nih.gov

Dr. Berman received her B.S. degree from the University of Rochester and her M.D. from St. Louis University Medical School. She completed her medical internship at Washington University in St. Louis and had residency training in psychiatry at the University of California at San Diego. Dr. Berman also completed residency training in nuclear medicine at the NIH Warren G. Magnusen Clinical Center and is board certified in both psychiatry and nuclear medicine. She has received the A.E. Bennett Award for Neuropsychiatric Research of the Society of Biological Psychiatry. Dr. Berman's group uses a variety of neuroimaging techniques to investigate the neurobiology of neuropsychiatric disorders (such as schizophrenia) and genetic diseases (such as Williams Syndrome) that affect cognition.

We use functional neuroimaging Functional and structural MRI, PET, and others) to map brain activity and neurochemical mechanisms associated with normal higher cognitive function as well as dysfunction in neuropsychiatric illnesses such as schizophrenia, illnesses having genetic sources of cognitive dysfunction such as Williams syndrome, and other conditions impacting cognition such as normal aging. We also study the effects of gonadal steroid hormones on brain function.

Aaron Bonner-Jackson
Research Assistant
Brad Buchsbaum, Ph.D.
Postdoctoral Fellow
Jean-Claude Dreher, Ph.D.
Postdoctoral Fellow
J. Kippenhan, Ph.D.
Special Expert
Philip Kohn
Special Expert
Andreas Meyer-Lindenberg, M.D.
Staff Clinician
Rosanna Olsen
Research Assistant

1) Dreher JC and Berman KF (2002)

Fractionating the neural substrate of cognitive control processes
PNAS: Proceedings of the National Academy of Sciences , 99

2) Meyer-Lindenberg A, Miletich RW, Kohn P, Esposito G, Carson RE, Quarantelli M, Weinberger DR, Berman KF (2002)

Prefrontal cortex dysfunction predicts exaggerated striatal dopamine uptake in schizophrenia
Nature Neuroscience, 5, 1809-17

3) Meyer-Lindenberg A, Ziemann U, Hajak G, Cohen L, Berman KF (2002)

Transitions between unstable and stable dynamical states in the human brain
PNAS: Proceedings of the National Academy of Sciences, 99

4) Meyer-Lindenberg A, Poline J-B, Kohn P, Holt JL, Egan MF, Weinberger DR, Berman KF (2001)

Evidence for altered cortical functional connectivity during working memory in schizophrenia
American Journal of Psychiatry, 158(11)

5) Esposito G, Kirkby BS, Van Horn JD, Ellmore TM, Berman KF (1999)

Context-dependent, neural system-specific neurophysiological correlates of aging: mapping PET correlates during cognitive activation
Brain, 122, 963-979

6) Berman KF, Schmidt PJ, Rubinow DR, Danaceau MA, Van Horn JD, Esposito E, Ostrem JL, Weinberger DR (1997)

Modulation of cognition-specific cortical activity by gonadal steroids: A PET study in women
PNAS, 94, 8836-8841

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