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Senior Investigator

Eva Mezey, M.D., Ph.D.

Independant Studies and Units, NIDCR
Building 36 Room 3D-10
36 Convent Drive
Bethesda MD 20892-
Office: (301) 435-5635

Fax: (301) 435-5465
mezeye@mail.nih.gov

Dr. Eva M. Mezey received her M.D. in 1975 from the Semmelweis University Medical School, and her Ph.D. in 1982 from the National Academy of Sciences in Budapest, Hungary. She completed post-doctoral training in the Department of Anatomy in Budapest under the guidance of Drs. John Szentagothai and Miklos Palkovits, and in the Department of Pharmacology in Utrecht (The Netherlands) under the supervision of Dr. David De Wied. In 1982, Dr. Mezey joined the NIMH to study neuroendocrine regulatory mechanisms and in 2004 moved to the NIDCR to become the Head of the Adult Stem Cell Research Section. Her laboratory is currently studying the process by which bone marrow cells differentiate into neurons and glia within the CNS.



Differentiation of bone marrow mesenchymal and hematopoetic stem cells into neuronal elements.

Identification of factors that draw stem cells into the brain and direct their differentiation there.

Characterization of receptors on stem cells that might induce migration, proliferation, and/or differentiation.

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  • Arne Hansen, M.D.
    Postdoctoral Fellow
    (301) 594-9445

  • Sharon Key
    Research Assistant
    (301) 496-3862

  • Ildiko Szalayova
    Research Assistant
    (301) 594-9442

  • Zsuzsanna Toth, Ph.D.
    Biologist
    (301) 435-5629

  • 1) Mezey, E (2004)
  • On Bone Marrow Cells and Openmindedness.
  • Stem Cells and Development , 13, 147-152
  • 2) Mezey E, Sharon Key, Georgia Vogelsang, Ildiko Szalayova, G. David Lange, and Barbara Crain (2003)
  • Transplanted bone marrow generates new neurons in human brains
  • PNAS , 100, 1364-1369
  • 3) Mezey, E, Nagy, A, Szalayova, I,Key, S., Bratincsak, A, Baffi, J, Shahar, T (2003)
  • Comment on Comment on "Failure of bone marrow cells to transdifferentiate into neural cells in vivo"
  • Science, 299(5610), 1184
  • 4) Tran S D, S R Pillemer, A Dutra, A J Barrett, M J Brownstein, S Key, E Pak, R A Leakan, A Kingman, K M Yamada, B J Baum and E Mezey. (2003)
  • Differentiation of human bone marrow-derived cells into buccal epithelial cells in vivo: a molecular analytical study
  • Lancet, 360, 1084-1088
  • 5) Mezey E, Chandross, K.J., Harta Gy, Maki R. A., McKercher S. R. (2000)
  • Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow.
  • Science , 290, 1775-1779
  • 6) Buckley, N., Harta, Gy., Hansson, S., Mezey, E. (1998)
  • Distribution of CB1 and CB2 receptors in the developing rat embryo.
  • Neuroscience , 82, 1131-1149
  • 7) Eglitis, M., Mezey, E. (1997)
  • Hematopoietic cells differentiate into astroglia in the brains of adult mice
  • PNAS, 94, 4080-4085
  • 8) Mezey, E., Palkovits, M. (1982)
  • Two-way transport in the hypothalamohypophyseal system.
  • Frontiers in Neuroendocrinology, 7, 1-29
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