Senior Investigator
Carson
C.
Chow,
Ph.D.
Laboratory of Biological Modeling
Dr. Chow received a Bachelor of Applied Science from the University of Toronto and a PhD in theoretical physics from the Massachusetts Institute of Technology in 1992. After his doctoral training he held a postdoctoral fellowship in nonlinear dynamics at the University of Colorado. In 1994, he switched fields to theoretical biology and neuroscience and obtained further postdoctoral training at Boston University, first with Jim Collins and then with Nancy Kopell. He took a faculty position in the Department of Mathematics at the University of Pittsburgh in 1998, rising to the level of Associate Professor before moving to NIH in 2004. In 1999 he was awarded an Alfred P. Sloan Research Fellowship. His current research focus is in theoretical biological and neuroscience, particularly in areas applicable to the control of feeding and metabolism.

1) A. Milac, A. Anishkin, S.N. Fatakia, C.C. Chow, H.R. Guy and S. Sukharev (2011)

Structural models of TREK channels and their gating mechanism
 Channels , 5:1, 2333

2) S. Vattikuti and C.C. Chow (2010)

A computational model for cerebral cortical dysfunction in Autism Spectrum Disorders
 Biol Psychiatry, 67, 6726798

3) M.A. Buice, J.D. Cowan, and C.C. Chow (2010)

Systematic Fluctuation Expansion for Neural Network Activity Equations
 Neural Comp., 22, 377426

4) S. Fatakia, S. Costanzi, and C.C. Chow (2009)

Identification of a common binding cavity for G proteincoupled receptors using mutual information and graph theory
 PLoS ONE , 4(3), e4681

5) G.M. Constantine, J. Bartels, C.C. Chow, G. Clermont, Y. Vodovotz (2009)

A linear code parameter search algorithm with applications to immunology
 Computational Optimization and Applications, 42, 155171

6) J. Day, J. Rubin, and C.C. Chow (2009)

Competition between transients in the rate of approach to a fixed point
 SIAM J. Appl. Dyn. Sys , 8, 1523

7) K.D. Hall, M. Dore, J. Guo, and C.C. Chow (2009)

The progressive increase of food waste in America
 PLoS ONE, 4(11), e7940

8) L.A. Furchtgott, C.C. Chow, V. Periwal (2009)

A model of liver regeneration
 Biophysical Journal , 96, 392635

9) R. Kumar, CC Chow, JD Bartels, G. Clermont, Y. Vodovotz (2008)

A mathematical simulation of the inflammatory response to anthrax infection
 Shock , 29, 104111

10) V. Periwal, C.C. Chow, R.N. Bergman, M. Ricks, G.L. Vega, and A.E. Sumner (2008)

Evaluation of quantitative models of the effect of insuln on lipolysis and glucose disposal
 Am J Physiol: Regulatory Integrative Comp Physiol, 295 , R1089R1096

11) C.C. Chow and K.D. Hall (2008)

The dynamics of human body weight change
 PLoS Computational Biology, 4, e1000045

12) M.A. Buice and C.C. Chow (2007)

Correlations, fluctuations and stability of a finitesize network of coupled oscillators
 Phys. Rev. E , 76, 031118

13) E. Hildebrand, M.A. Buice, and C.C. Chow (2007)

Kinetic theory of coupled oscillators
 Physical Review Letters , 98, 054101

14) H. Soula and C.C. Chow (2007)

Stochastic dynamics of a finitesize spiking neural network
 Neural Comp., 19, 326292

15) M. Shafi, Y. Zhou, J. Quintana, C. Chow, J. Fuster, and M. Bodner (2007)

Variability in neuronal activity in primate cortex during working memory tasks
 Neuroscience, 146, 10821108

16) Carson C. Chow (2007)

Multiple scale analysis
 Scholarpedia, 2(10), 1617

17) K.D. Hall, H.L. Bain and C.C. Chow (2007)

How adaptations of substrate utilization regulate body composition
 International Journal of Obesity, 31, 137883

18) C.C. Chow and S. Coombes (2006)

Existence and Wandering of bumps in a spiking neural network model
 SIAM Journal on Applied Dynamical Systems , 5, 552574

19) J. Day, J. Rubin, Y. Vodovotz, PhD; C.C. Chow, A.M. Reynolds, G. Clermont (2006)

A reduced mathematical model of the acute inflammatory response: Capturing scenarios of repeated endotoxin administration
 Journal of Theoretical Biology, 242, 237256

20) Y. Kim, Y. Sun, C.C. Chow, Y.G. Pommier, and S.S. Simons (2006)

Effects of Acetylation, Polymerase Phosphorylation, and DNA Unwinding on Glucocorticoid Receptor Transactivation
 Journal of Steroid Biochemistry and Molecular Biology , 100, 317

21) V. Periwal and C.C. Chow (2006)

Patterns in food intake correlate with body mass index
 American Journal of Physiology: Endocrinology and Metabolism, 291, 929936

22) Y. Vodovotz, C.C. Chow, J. Bartels, C. Lagoa, J.M. Prince, R.M. Levy, R. Kumar, J. Day, J. Rubin, G. Constantine, T.R. Billiar, M.P. Fink, G. Clermont (2006)

In silico models of acute inflammation in animals
 Shock , 26, 23544

23) S. Moldakarimov, J.E. Rollenhagen, C.R. Olson, and C.C. Chow (2005)

Competitive dynamics in cortical responses to visual stimuli
 Journal of Neurophysiology , 94, 33883396

24) C.C. Chow, G. Clermont, R. Kumar, C. Lagoa, Z. Tawadrous, D. Gallo, B. Betten, J. Bartels, G. Constantine, M.P. Fink, T.R. Billiar, and Y. Vodovotz (2005)

The acute inflammtory response in diverse shock states
 Shock, 24, 484

25) J.E. Rubin, R.C. Gerkin, G.Q. Bi, and C.C. Chow (2005)

Calcium time course as a signal for spiketiming dependent plasticity
 Journal of Neurophysiology , 93, 26002613

29) G. Clermont, J. Bartels, R. Kumar, G. Constantine, Y. Vodovotz, and C. Chow (2004)

In silico design of clinical trials: A method coming of age
 Critical Care Medicine, 32, 20612070

31) Y. Vodovotz, P.K. Kim, E.Z. Bagci, G.B. Ermentrout, C.C. Chow, I. Bahar, T.R. Billiar (2004)

Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies
 Curr Mol Med, 32, 753762
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