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Senior Investigator

Carson C. Chow, Ph.D.

Laboratory of Biological Modeling, NIDDK
Building 12A Room 4007
12A South Drive MSC5621
Bethesda MD 20892-5621
Office: (301) 402-8250
Lab: (301) 402-0535

carsonc@mail.nih.gov

Dr. Chow received a Bachelor of Applied Science from the University of Toronto and a PhD in theoretical physics from the Massachusetts Institute of Technology in 1992. After his doctoral training he held a postdoctoral fellowship in nonlinear dynamics at the University of Colorado. In 1994, he switched fields to theoretical biology and neuroscience and obtained further postdoctoral training at Boston University, first with Jim Collins and then with Nancy Kopell. He took a faculty position in the Department of Mathematics at the University of Pittsburgh in 1998, rising to the level of Associate Professor before moving to NIH in 2004. In 1999 he was awarded an Alfred P. Sloan Research Fellowship. His current research focus is in theoretical biological and neuroscience, particularly in areas applicable to the control of feeding and metabolism.



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  • 1) A. Milac, A. Anishkin, S.N. Fatakia, C.C. Chow, H.R. Guy and S. Sukharev (2011)
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  • Structural models of TREK channels and their gating mechanism
  • Channels , 5:1, 23-33
  • 2) S. Vattikuti and C.C. Chow (2010)
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  • A computational model for cerebral cortical dysfunction in Autism Spectrum Disorders
  • Biol Psychiatry, 67, 672-6798
  • 3) M.A. Buice, J.D. Cowan, and C.C. Chow (2010)
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  • Systematic Fluctuation Expansion for Neural Network Activity Equations
  • Neural Comp., 22, 377-426
  • 4) S. Fatakia, S. Costanzi, and C.C. Chow (2009)
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  • Identification of a common binding cavity for G protein-coupled receptors using mutual information and graph theory
  • PLoS ONE , 4(3), e4681
  • 5) G.M. Constantine, J. Bartels, C.C. Chow, G. Clermont, Y. Vodovotz (2009)
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  • A linear code parameter search algorithm with applications to immunology
  • Computational Optimization and Applications, 42, 155-171
  • 6) J. Day, J. Rubin, and C.C. Chow (2009)
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  • Competition between transients in the rate of approach to a fixed point
  • SIAM J. Appl. Dyn. Sys , 8, 1523
  • 7) K.D. Hall, M. Dore, J. Guo, and C.C. Chow (2009)
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  • The progressive increase of food waste in America
  • PLoS ONE, 4(11), e7940
  • 8) L.A. Furchtgott, C.C. Chow, V. Periwal (2009)
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  • A model of liver regeneration
  • Biophysical Journal , 96, 3926-35
  • 9) R. Kumar, CC Chow, JD Bartels, G. Clermont, Y. Vodovotz (2008)
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  • A mathematical simulation of the inflammatory response to anthrax infection
  • Shock , 29, 104-111
  • 10) V. Periwal, C.C. Chow, R.N. Bergman, M. Ricks, G.L. Vega, and A.E. Sumner (2008)
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  • Evaluation of quantitative models of the effect of insuln on lipolysis and glucose disposal
  • Am J Physiol: Regulatory Integrative Comp Physiol, 295 , R1089-R1096
  • 11) C.C. Chow and K.D. Hall (2008)
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  • The dynamics of human body weight change
  • PLoS Computational Biology, 4, e1000045
  • 12) M.A. Buice and C.C. Chow (2007)
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  • Correlations, fluctuations and stability of a finite-size network of coupled oscillators
  • Phys. Rev. E , 76, 031118
  • 13) E. Hildebrand, M.A. Buice, and C.C. Chow (2007)
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  • Kinetic theory of coupled oscillators
  • Physical Review Letters , 98, 054101
  • 14) H. Soula and C.C. Chow (2007)
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  • Stochastic dynamics of a finite-size spiking neural network
  • Neural Comp., 19, 3262-92
  • 15) M. Shafi, Y. Zhou, J. Quintana, C. Chow, J. Fuster, and M. Bodner (2007)
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  • Variability in neuronal activity in primate cortex during working memory tasks
  • Neuroscience, 146, 1082-1108
  • 16) Carson C. Chow (2007)
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  • Multiple scale analysis
  • Scholarpedia, 2(10), 1617
  • 17) K.D. Hall, H.L. Bain and C.C. Chow (2007)
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  • How adaptations of substrate utilization regulate body composition
  • International Journal of Obesity, 31, 1378-83
  • 18) C.C. Chow and S. Coombes (2006)
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  • Existence and Wandering of bumps in a spiking neural network model
  • SIAM Journal on Applied Dynamical Systems , 5, 552-574
  • 19) J. Day, J. Rubin, Y. Vodovotz, PhD; C.C. Chow, A.M. Reynolds, G. Clermont (2006)
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  • A reduced mathematical model of the acute inflammatory response: Capturing scenarios of repeated endotoxin administration
  • Journal of Theoretical Biology, 242, 237-256
  • 20) Y. Kim, Y. Sun, C.C. Chow, Y.G. Pommier, and S.S. Simons (2006)
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  • Effects of Acetylation, Polymerase Phosphorylation, and DNA Unwinding on Glucocorticoid Receptor Transactivation
  • Journal of Steroid Biochemistry and Molecular Biology , 100, 3-17
  • 21) V. Periwal and C.C. Chow (2006)
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  • Patterns in food intake correlate with body mass index
  • American Journal of Physiology: Endocrinology and Metabolism, 291, 929-936
  • 22) Y. Vodovotz, C.C. Chow, J. Bartels, C. Lagoa, J.M. Prince, R.M. Levy, R. Kumar, J. Day, J. Rubin, G. Constantine, T.R. Billiar, M.P. Fink, G. Clermont (2006)
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  • In silico models of acute inflammation in animals
  • Shock , 26, 235-44
  • 23) S. Moldakarimov, J.E. Rollenhagen, C.R. Olson, and C.C. Chow (2005)
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  • Competitive dynamics in cortical responses to visual stimuli
  • Journal of Neurophysiology , 94, 3388-3396
  • 24) C.C. Chow, G. Clermont, R. Kumar, C. Lagoa, Z. Tawadrous, D. Gallo, B. Betten, J. Bartels, G. Constantine, M.P. Fink, T.R. Billiar, and Y. Vodovotz (2005)
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  • The acute inflammtory response in diverse shock states
  • Shock, 24, 4-84
  • 25) J.E. Rubin, R.C. Gerkin, G.-Q. Bi, and C.C. Chow (2005)
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  • Calcium time course as a signal for spike-timing dependent plasticity
  • Journal of Neurophysiology , 93, 2600-2613
  • 29) G. Clermont, J. Bartels, R. Kumar, G. Constantine, Y. Vodovotz, and C. Chow (2004)
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  • In silico design of clinical trials: A method coming of age
  • Critical Care Medicine, 32, 2061-2070
  • 31) Y. Vodovotz, P.K. Kim, E.Z. Bagci, G.B. Ermentrout, C.C. Chow, I. Bahar, T.R. Billiar (2004)
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  • Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies
  • Curr Mol Med, 32, 753-762
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