Investigator:
David
R. Sibley Affiliation:
Molecular
Neuropharmacology Section, NINDS Position
Type: Postdoctoral
Fellowship Labs Web Page:
http://neuroscience.nih.gov/Lab.asp?Org_ID=67
Description:
A
position is available for investigating the cellular and molecular
biological characteristics of dopamine receptors. Projects include
investigating the cell biology, pharmacology, and regulation of these
receptors in clonal cell lines that have been stably transfected with
receptor cDNAs. Areas of particular interest involve studying receptor
structure/function/pharmacology relationships, receptor-effector coupling
mechanisms, G protein interactions, and biochemical/molecular mechanisms
of receptor desensitization. Additional projects involve the cloning
of genes encoding proteins which interact with dopamine receptors,
site-directed mutagenesis and receptor chimera studies, analysis and
characterization of receptor expression in both normal and pathophysiological
states. Transgenic and receptor "knock-out" animal projects are also
in progress.
Application
Instructions:
Please
send a letter describing your research interests, your curriculum
vitae and the names of three references to:
David R. Sibley, Ph.D.
Molecular Neuropharmacology Section, NINDS, NIH
Building 10, Room 5C108
10 Center Drive, MSC 1406
Bethesda, MD 20892-1406
