Molecular Neurophysiology Section - Publications

• Lopez-Rodriguez A, Holmgren M (2012) Restoration of proper trafficking to the cell surface for membrane proteins harboring cysteine mutations. , PLoS One. 2012;7(10), e47693. Full Text/Abstract

• Gadsby, D.C., Bezanilla, F., Rakowski, R.F., De Weer, P. and Holmgren (2012) The dynamic relationships between the three events that release individual Na+ ions from the Na+/K+-ATPase, Nature Communications 3, 669 doi:1038/ncomms1673. Full Text/Abstract

• Castillo J.P., De Giorgis D., Basilio, D., Gadsby, D.C., Rosenthal, J.J., Latorre, R., Holmgren, M., Bezanilla, (2011) Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the axon of the Humboldt squid. , Proc. Nat. Acad. Sci. USA 108, 20556-20561. Full Text/Abstract

• Gonzalez, C., Lopez-Rodriguez, A., Srikumar, D., Rosenthal, J.J.C. and Holmgren, M. (2011) Editing of human KV1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity., Nat. Commun. 2, 436 doi: 10.1038/ncomms1446. Full Text/Abstract

• Sandtner, W., Egwolf, B., Khalili-Araghi, F., Sanchez-Rodriguez, J.E., Roux, B., Bezanilla, F. and Holmgren, M. (2011) Ouabain binding site in a functioning Na+/K+-ATPase. , J. Biol. Chem. 286, 38177-38183.. Full Text/Abstract

• Galarza, G. Soto, S.I., Holmgren M. and Rosenthal, J.J.C (2011) Physiological Adaptation of an Antarctic Na+/K+-ATPase to the cold., J. Exp. Biol. 214, 2164-2174. Full Text/Abstract

• Colina, C., Palavicini, J.P., Srikumar, D., Holmgren, M. and Rosenthal, J.J.C (2010) Regulation of Na+/K+ ATPase transport velocity by RNA editing., PLoS Biol. 8, e1000540. Full Text/Abstract

• Contreras, J.E., Chen, J., Lau, A.Y., Jogini, V., Roux, B. and Holmgren, M (2010) Voltage profile along the permeation pathway of an open channel., Biophys. J. 99, 2863-2869. Full Text/Abstract

• Contreras, J.E. Srikumar, D. and Holmgren, M. (2008) Gating at the selectivity filter in cyclic nucleotide-gated channels, PNAS 105, 3310-3314. Full Text/Abstract

• Colina, C., J.J.C. Rosenthal, J.A. DeGiorgis, D. Srikumar, N. Iruku& M. Holmgren (2007) Structural basis of Na+/K+-ATPase adaptation to marine environments, Nature Structural Molecular Biology 14, 427-431. Full Text/Abstract

• Rakowski, R.F., P. Artigas, F. Palma, M. Holmgren, P. De Weer, & D.C. Gadsby (2007) Sodium Flux Ratio in Na/K Pump-Channels Opened by Palytoxin, Journal of General Physiology 130, 41-54. Full Text/Abstract

• Holmgren, M. and Rakowski, RF. (2006) Charge Translocation by the Na+/K+ Pump under Na+/Na+ Exchange Conditions: Intracellular Na+ Dependence, Biophys. J. 90, 1607-16. Full Text/Abstract

• Contreras, JE and Holmgren, M. (2006) Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate., J. Gen. Physiol. 127, 481-94. Full Text/Abstract

• Bhalla, T., Rosenthal, JJC, Holmgren, M., and Reenan, R. (2004) Control of Human Potassium Channel Inactivation by Editing of a Small mRNA Hairpin, Nature Structural & Molecular Biology 11, 950-956. Full Text/Abstract

• Holmgren, Miguel (2003) Influence of Permeant Ions on Gating in Cyclic Nucleotide-gated Channels, J. Gen Physiol 121, 61-72. Full Text/Abstract

• Soler-Llavina GJ, Holmgren M, and Swartz KJ (2003) Defining the Conductance of the Closed State in a Voltage-Gated K+ Channel, Neuron 38, 61-67. Full Text/Abstract

• Holmgren M, Wagg J, Bezanilla F, Rakowski RF, De Weer P and Gadsby DC (2000) Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase, Nature 403(6772), 898-901. Full Text/Abstract

• del Camino D, Holmgren M, Liu Y, Yellen G. (2000) Blocker protection in the pore of a voltage-gated K+ channel and its structural implications, Nature 403(6767), 321-5. Full Text/Abstract

• Holmgren M, Shin KS, Yellen G (1998) The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge, Neuron 21(3), 617-21. Full Text/Abstract

• Liu Y, Holmgren M, Jurman ME, Yellen G. (1997) Gated access to the pore of a voltage-dependent K+ channel, Neuron 19(1), 175-84. Full Text/Abstract

• Holmgren M, Smith PL, Yellen G. (1997) Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating, J Gen Physiol 109(5), 527-35. Full Text/Abstract

• Holmgren M, Jurman ME, Yellen G. (1996) N-type inactivation and the S4-S5 region of the Shaker K+ channel, :J Gen Physiol 108(3), 195-206. Full Text/Abstract

• Holmgren M, Liu Y, Xu Y, Yellen G. (1996) On the use of thiol-modifying agents to determine channel topology, Neuropharmacology 35(7), 797-804. Full Text/Abstract

• Holmgren M, Rakowski RF. (1994) Pre-steady-state transient currents mediated by the Na/K pump in internally perfused Xenopus oocytes, Biophys J 66(3 Pt 1), 912-22. Full Text/Abstract