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| Stephan D. Brenowitz, Ph.D., Investigator |
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Dr. Brenowitz received a B.A. degree in Molecular Biology from the University of California - Berkeley and a Ph.D. in Neuroscience from the University of Wisconsin - Madison, where he studied plasticity at endbulb synapses of the cochlear nucleus in the laboratory of Laurence Trussell. During a postdoctoral fellowship with Wade Regehr at Harvard Medical School, he investigated mechanisms of endocannabinoid signaling and its modulatory effects on synaptic transmission in the cerebellum. Dr. Brenowitz joined the NIDCD as an Investigator in 2007. His laboratory explores mechanisms of synaptic transmission and plasticity in the auditory system using electrophysiology, two-photon imaging and molecular techniques.
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Staff:
Selected Recent Publications:
Ma WL, Brenowitz SD (2011) Single-neuron Recordings from Unanesthetized Mouse Dorsal Cochlear Nucleus, J Neurophysiol. Nov 9. [Epub ahead of print] PubMed PMID: 22072506.
Sedlacek M, Tipton PW, Brenowitz SD (2011) Sustained firing of cartwheel cells in the dorsal cochlear nucleus evokes endocannabinoid release and retrograde suppression of parallel fiber synapses , J Neurosci. Nov 2;31(44), 15807-17. PubMed PMID: 22049424.
Wang PY, Petralia RS, Wang YX, Wenthold RJ, Brenowitz SD (2011) Functional NMDA receptors at axonal growth cones of young hippocampal neurons, J. Neurosci 31(25), 9289-97.
Wagner W, Brenowitz SD, Hammer JA 3rd (2011) Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons, Nat Cell Biol 13(1), 40-8.
Puligilla C, Dabdoub A, Brenowitz SD, Kelley MW (2010) Sox2 induces neuronal formation in the developing mammalian cochlea, J Neurosci 30(2), 714-22.
Brenowitz SD, Regehr WG. (2007) Reliability and heterogeneity of calcium signaling at single presynaptic boutons of cerebellar granule cells, J Neurosci Jul 25;27(30), 7888-98.
Full Text/Abstract
Brenowitz SD, Best AR, Regehr WG (2006) Sustained elevation of dendritic calcium evokes widespread endocannabinoid release and suppression of synapses onto cerebellar Purkinje cells, J Neurosci Jun 21;26(25), 6841-50.
Full Text/Abstract
All Selected Publications
Contact Information:
Dr. Stephan D. Brenowitz
Section on Synaptic Transmission, NIDCD
Rm 4152 / Bldg 50
50 South Dr.
Bethesda, MD 20892-
Telephone: (301) 496-6069 (office),
Email: brenowitzs@nidcd.nih.gov
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