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Okihide Hikosaka, M.D., Ph.D., Senior Investigator

Dr. Hikosaka received his M.D. and Ph.D. from University of Tokyo where he worked in the laboratory of Hiroshi Shimazu on the brainstem vestibulo-oculomotor system. He did postdoctoral research with Robert Wurtz at the Laboratory of Sensorimotor Research, NEI on the role of the substantia nigra pars reticulata in the control of saccadic eye movements. He became Assistant Professor at Toho University School of Medicine (Tokyo) in 1979, Full Professor at National Institute of Physiological Sciences (Okazaki) in 1988, and Full Professor at Juntendo University School of Medicine (Tokyo) in 1993. In 2002, he returned to the Laboratory of Sensorimotor Research, NEI as a Senior Investigator and Chief of the Section of Neuronal Networks. He was elected to the American Academy of Arts & Sciences in 2011. His main interest is the neural mechanisms of voluntary behavior. His laboratory studies the mechanisms of motivation, learning, skill, decision-making, attention, and oculomotor control.
Photo of Okihide Hikosaka, M.D., Ph.D., Senior Investigator

Staff:



Selected Recent Publications:
  • Hikosaka O, Yamamoto S, Yasuda M, Kim HF (2013) Why skill matters., Trends Cogn Sci 17(9), 434-41. Full Text/Abstract

  • Hong S, Hikosaka O (2013) Diverse sources of reward value signals in the basal ganglia nuclei transmitted to the lateral habenula in the monkey., Front Hum Neurosci 7, 778. Full Text/Abstract

  • Kim HF, Hikosaka O (2013) Distinct basal ganglia circuits controlling behaviors guided by flexible and stable values. , Neuron 79(5), 1001-10. Full Text/Abstract

  • Terao Y, Fukuda H, Ugawa Y, Hikosaka O (2013) New perspectives on the pathophysiology of Parkinson's disease as assessed by saccade performance: A clinical review., Clin Neurophysiol 124(8), 1491-506. Full Text/Abstract

  • Yamamoto S, Kim HF, Hikosaka O (2013) Reward value-contingent changes of visual responses in the primate caudate tail associated with a visuomotor skill., J. Neurosci 33(27), 11227-38. Full Text/Abstract

  • Monosov IE, Hikosaka O (2013) Selective and graded coding of reward uncertainty by neurons in the primate anterodorsal septal region. , Nat Neurosci 16(6), 756-62. Full Text/Abstract

  • Daye PM, Monosov IE, Hikosaka O, Leopold DA, Optican LM (2013) pyElectrode: an open-source tool using structural MRI for electrode positioning and neuron mapping., J Neurosci Methods 213(1), 123-31. Full Text/Abstract

All Selected Publications


Contact Information:

Dr. Okihide Hikosaka
Section of Neuronal Networks
Laboratory of Sensorimotor Research, NEI
Building 49, Room 2A50
49 Convent Drive, MSC 4435
Bethesda, MD 20892-2235

Telephone: (301) 402-7959 (office), (301) 496-9375 (laboratory), (301) 402-0511 (fax)
Email: oh@lsr.nei.nih.gov

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