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| Okihide Hikosaka, M.D., Ph.D., Senior Investigator |
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Dr. Hikosaka received his M.D. and Ph.D. from University of Tokyo where he worked in the laboratory of Hiroshi Shimazu on the brainstem vestibulo-oculomotor system. He did postdoctoral research with Robert Wurtz at the Laboratory of Sensorimotor Research, NEI on the role of the substantia nigra pars reticulata in the control of saccadic eye movements. He became Assistant Professor at Toho University School of Medicine (Tokyo) in 1979, Full Professor at National Institute of Physiological Sciences (Okazaki) in 1988, and Full Professor at Juntendo University School of Medicine (Tokyo) in 1993. In 2002, he returned to the Laboratory of Sensorimotor Research, NEI as a Senior Investigator and Chief of the Section of Neuronal Networks. He was elected to the American Academy of Arts & Sciences in 2011. His main interest is the neural mechanisms of voluntary behavior. His laboratory studies the mechanisms of motivation, learning, skill, decision-making, attention, and oculomotor control.
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Staff:
- Ethan Bromberg-Martin, Ph.D., Postdoctoral Fellow bromberge@nei.nih.gov
- Ali Ghazizadeh Ehsaei, Ph.D., Postdoctoral Fellow ali.ghazizadehehsaei@nih.gov
- Hyoung Kim, Ph.D., Postdoctoral Fellow hyoungk@mail.nih.gov
- Ilya Monosov, Ph.D., Postdoctoral Fellow monosovi@nei.nih.gov
- Masaharu Yasuda, Ph.D., Postdoctoral Fellow yasudama@nei.nih.gov
Selected Recent Publications:
Bromberg-Martin ES, Matsumoto M, Nakahara H, Hikosaka O. (2010) Multiple timescales of memory in lateral habenula and dopamine neurons., Neuron 12;67(3), 499-510.
Full Text/Abstract
Hikosaka O. (2010) The habenula: from stress evasion to value-based decision-making., Nat Rev Neurosci. 11(7), 503-12.
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Bromberg-Martin ES, Hikosaka O, Nakamura K (2010) Coding of task reward value in the dorsal raphe nucleus., J Neurosci 30, 6262-72.
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Yugeta A, Terao Y, Fukuda H, Hikosaka O, Yokochi F, Okiyama R, Taniguchi M, Takahashi H, Hamada I, Hanajima R, Ugawa Y (2010) Effects of STN stimulation on the initiation and inhibition of saccade in Parkinson disease., Neurology 74, 743-748.
Hikosaka O, Isoda M (2010) Switching from automatic to controlled behavior: cortico-basal ganglia mechanisms., Trends Cogn Sci. 14(4), 154-61.
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Bromberg-Martin ES, Matsumoto M, Hikosaka O. (2010) Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons., Neuron 15;67(1), 144-55.
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Bromberg-Martin ES, Matsumoto M, Hong S, Hikosaka O. (2010) A pallidus-habenula-dopamine pathway signals inferred stimulus values., J Neurophysiol 104(2), 1068-76.
Full Text/Abstract
All Selected Publications
Contact Information:
Dr. Okihide Hikosaka
Section of Neuronal Networks
Laboratory of Sensorimotor Research, NEI
Building 49, Room 2A50
49 Convent Drive, MSC 4435
Bethesda, MD 20892-2235
Telephone: (301) 402-7959 (office),
(301) 496-9375 (laboratory),
(301) 402-0511 (fax)
Email: oh@lsr.nei.nih.gov
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