Neuroscience at HIH Home
NINDS Home NIMH Home NICHD Home NIDCD Home NEI Home NIDCR Home NIA Home NIAAA Home NIDA Home NHGRI Home NIEHS Home NCI Home
National Institutes of Health - Neuroscience at HIH Link to NIH
Link to About Us
Link to Faculty
Link to Areas of Research
Link to Seminars
Link to Interest Groups
Link to Post-doctoral Openings
Link to Home
 

Okihide Hikosaka, M.D., Ph.D., Senior Investigator

Dr. Hikosaka received his M.D. and Ph.D. from University of Tokyo where he worked in the laboratory of Hiroshi Shimazu on the brainstem vestibulo-oculomotor system. He did postdoctoral research with Robert Wurtz at the Laboratory of Sensorimotor Research, NEI on the role of the substantia nigra pars reticulata in the control of saccadic eye movements. He became Assistant Professor at Toho University School of Medicine (Tokyo) in 1979, Full Professor at National Institute of Physiological Sciences (Okazaki) in 1988, and Full Professor at Juntendo University School of Medicine (Tokyo) in 1993. In 2002, he returned to the Laboratory of Sensorimotor Research, NEI as a Senior Investigator and Chief of the Section of Neuronal Networks. He was elected to the American Academy of Arts & Sciences in 2011. His main interest is the neural mechanisms of voluntary behavior. His laboratory studies the mechanisms of motivation, learning, skill, decision-making, attention, and oculomotor control.
Photo of Okihide Hikosaka, M.D., Ph.D., Senior Investigator

Staff:



Selected Recent Publications:
  • Bromberg-Martin ES, Matsumoto M, Nakahara H, Hikosaka O. (2010) Multiple timescales of memory in lateral habenula and dopamine neurons., Neuron 12;67(3), 499-510. Full Text/Abstract

  • Hikosaka O. (2010) The habenula: from stress evasion to value-based decision-making., Nat Rev Neurosci. 11(7), 503-12. Full Text/Abstract

  • Bromberg-Martin ES, Hikosaka O, Nakamura K (2010) Coding of task reward value in the dorsal raphe nucleus., J Neurosci 30, 6262-72. Full Text/Abstract

  • Yugeta A, Terao Y, Fukuda H, Hikosaka O, Yokochi F, Okiyama R, Taniguchi M, Takahashi H, Hamada I, Hanajima R, Ugawa Y (2010) Effects of STN stimulation on the initiation and inhibition of saccade in Parkinson disease., Neurology 74, 743-748.

  • Hikosaka O, Isoda M (2010) Switching from automatic to controlled behavior: cortico-basal ganglia mechanisms., Trends Cogn Sci. 14(4), 154-61. Full Text/Abstract

  • Bromberg-Martin ES, Matsumoto M, Hikosaka O. (2010) Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons., Neuron 15;67(1), 144-55. Full Text/Abstract

  • Bromberg-Martin ES, Matsumoto M, Hong S, Hikosaka O. (2010) A pallidus-habenula-dopamine pathway signals inferred stimulus values., J Neurophysiol 104(2), 1068-76. Full Text/Abstract

All Selected Publications


Contact Information:

Dr. Okihide Hikosaka
Section of Neuronal Networks
Laboratory of Sensorimotor Research, NEI
Building 49, Room 2A50
49 Convent Drive, MSC 4435
Bethesda, MD 20892-2235

Telephone: (301) 402-7959 (office), (301) 496-9375 (laboratory), (301) 402-0511 (fax)
Email: oh@lsr.nei.nih.gov

top

Home   |   Email List   |   Search   |   Contact Us   |   Privacy Notice   |   Disclaimer   |   Accessibility
Comments or questions about the website?
Send email to neuroscience@nih.gov