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David M. Lovinger, Ph.D., Senior Investigator

Dr. Lovinger received a B.A. in Psychology from the University of Arizona in 1981 and a Ph.D. in Psychology from Northwestern University in 1987. At Northwestern, he worked with Dr. Aryeh Routtenberg studying the roles of Protein Kinase C and its substrate, the GAP-43/F1 protein, in hippocampal long-term potentiation. His postdoctoral research at the NIAAA focused on the effects of alcohol on ligand-gated ion channels. In 1991 Dr. Lovinger moved to the Vanderbilt University School of Medicine as an Assistant Professor, where in 1998 he rose to the rank of Professor. At Vanderbilt he was also the Deputy Director for Biomedical Science and the Director of the Neuroscience Core within the Kennedy Center. Dr. Lovinger joined the NIAAA in 2001 as a Senior Investigator and Chief of the Laboratory of Integrative Neuroscience. His laboratory is currently studying the modulation and plasticity of synaptic transmission at corticostriatal synapses and the mechanisms by which abused substances effect synaptic transmission.
Photo of David M. Lovinger, Ph.D., Senior Investigator

Selected Recent Publications:
  • Bello, E., Mateo. Y., Gelman, D.M., Noain, D., Shin, J.H., Low, M.J., Alvarez, V.A., Lovinger., D.M. and Rubinstein. M. (2011) Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors, Nature Neuroscience 14(8), 1033-1038.

  • Mathur, B.N., Capik, N.A., Alvarez, V.A. and Lovinger, D.M. (2011) Serotonin-mediated long-term depression at corticostriatal synapse, J. Neurosci 31(20), 7402-11.

  • Adermark, L. and Lovinger, D.M. (2009) Frequency-dependent inversion of net striatal output by endocannabinoid-dependent plasticity at different synaptic inputs, J. Neurosci 29(5), 1375-1380.

  • Yin, H.H., Mulcare, S.P., Hilario, M.R.F., Clouse, E., Holloway, T., Davis, M.I., Hansson, A.C., Lovinger, D.M. and Costa, R.M. (2009) Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill, Nat. Neurosci 12(3), 333-341.

All Selected Publications


Contact Information:

Dr. David M. Lovinger
Clinical and Biological Research Unit
NIAAA
Building Park, Room 158H
12420 Parklawn Dr, MSC 8115
Bethesda, MD 20892-8115

Telephone: (301) 443-2445 (office), (301) 443-2445 (laboratory), (301) 480-1734 (fax)
Email: lovindav@mail.nih.gov

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