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Barry Horwitz, Ph.D., Senior Investigator

Dr. Horwitz received his B.A. degree from Washington University in St. Louis and his Ph.D. in physics from the University of Pennsylvania. After several years of teaching physics, he joined the NIA as a Senior Staff Fellow in the Laboratory of Neurosciences, headed by Stanley I. Rapoport. Dr. Horwitz's work focused on developing methods for using positron emission tomography to determine how different brain regions interact in human subjects. In 1989, he obtained tenure and in 1999 he joined the Language Section, NIDCD, as a Senior Investigator. In 2002, he became Chief of the Brain Imaging and Modeling Section of NIDCD. Dr. Horwitz's laboratory currently studies the neural basis of human cognition, especially auditory and language function, using functional brain imaging and computational neural modeling.
Photo of Barry        Horwitz, Ph.D., Senior Investigator

Staff:
Staff Photo for Brain Imaging and Modeling Section


Research Interests:
Current research focuses on understanding how the brain constructs networks of interacting regions (i.e., neural networks) to perform cognitive tasks, especially those associated with audition and language, and how these networks are altered in brain disorders. These issues are addressed by combining computational neuroscience techniques with functional neuroimaging data, obtained using fMRI, PET, or MEG. The network analysis methods allow us to evaluate how brain operations differ between tasks and between normal and patient populations. This research will allow us to ascertain which networks are dysfunctional, and the role neural plasticity plays in enabling compensatory behavior to occur. A unique aspect of our research is that most of the experiments we do are linked to our modeling, in that these experiments are performed to either acquire data for developing our models or else for testing them.


Selected Recent Publications:
  • Horwitz, B., Wise, R.J.S. (2008) PET research of language, Handbook of the Neuroscience of Language , 71-80.

  • Horwitz, B., Husain, F.T. (2007) Simulation frameworks for large-scale brain systems, Handbook of Brain Connectivity , 275-302.

  • Lee, L., Friston, K.J., Horwitz, B. (2006) Large-scale neural models and Dynamic Causal Modelling, NeuroImage 30, 1243-1254.

All Selected Publications


Contact Information:

Dr. Barry Horwitz
Brain Imaging and Modeling Section
Voice, Speech and Language Branch, NIDCD
Bldg. 10, Rm. 5D39
10 Center Drive, MSC 1402
Bethesda, MD 20892-1402

Telephone: (301) 594-7755 (office), (301) 480-5625 (fax)
Email: horwitzb@mail.nih.gov

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